SCHEMBL6413982

SCHEMBL6413982

CCC(Cl)(Cl)N1CC(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.41
TOP2A P11388 2/20 0.34
TOP2B Q02880 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PTGS1 P23219 2/20 0.32
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5827545 0.82 CRBN (0.38) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL18938260 0.79 CRBN (0.41) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL8614623 0.75 CRBN (0.38) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL3877149 0.73 CRBN (0.48) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL8082419 0.70 CRBN (0.44) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL20223130 0.70 CRBN (0.44) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL20956950 0.69 CRBN (0.42) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL17160562 0.68 CRBN (0.35) CRBNTOP2ATOP2BPTGS1LMNA
SCHEMBL20373877 0.67 CRBN (0.34) CRBNTOP2ATOP2BALDH1A1PTGS1
SCHEMBL22414473 0.64 CRBN (0.35) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1556547-A1 ADDITIVE AND METHOD FOR AVOIDING OR AT LEAST REDUCING DEPOSITS IN WATER BEARING AND/OR CONTACTING INDUSTRIAL SYSTEMS Pohlen, Alfred (LU) 2005-07-27 EP claimed
WO-2004031481-A1 ADDITIVE AND METHOD FOR AVOIDING OR AT LEAST REDUCING DEPOSITS IN WATER BEARING AND/OR CONTACTING INDUSTRIAL SYSTEMS POHLEN ALFRED (LU) 2004-04-15 WO claimed