Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436849 | 0.87 | KDM4E (0.61) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6436845 | 0.87 | KDM4E (0.61) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6419253 | 0.86 | PHGDH (0.57) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6419258 | 0.86 | PHGDH (0.57) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6435171 | 0.86 | BIRC5 (0.68) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6435175 | 0.86 | BIRC5 (0.68) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6421081 | 0.85 | MAPT (0.50) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6421076 | 0.85 | MAPT (0.50) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6435516 | 0.85 | KDM4E (0.66) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL6510185 | 0.84 | BIRC5 (0.50) | ALDH1A1KDM4EKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | 4SC AG (DE) | 2005-06-30 | — | — | US | disclosed |
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | NR5A2, NR1H2, NR2C2 | ALDH1A1 1119/4885KDM4E 3277/4885KMT2A 3640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.