Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 13/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414742 | 0.93 | MEN1 (0.36) | RPA1ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL6415959 | 0.91 | BIRC5 (0.42) | RPA1CSNK2A1CSNK2A2CSNK2BALDH1A1 | |
| SCHEMBL6432253 | 0.90 | RPA1 (0.44) | RPA1CSNK2A1CSNK2A2CSNK2BALDH1A1 | |
| SCHEMBL6417031 | 0.89 | CSNK2A1 (0.44) | CSNK2A1CSNK2A2CSNK2BALDH1A1TDO2 | |
| SCHEMBL6417016 | 0.89 | CSNK2A1 (0.44) | CSNK2A1CSNK2A2CSNK2BALDH1A1TDO2 | |
| SCHEMBL6419745 | 0.88 | PTPN1 (0.43) | CSNK2A1ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL6415096 | 0.86 | AURKA (0.38) | RPA1ALDH1A1TDO2POLBMAPT | |
| SCHEMBL6419747 | 0.84 | BIRC5 (0.43) | RPA1ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL6422204 | 0.83 | KDM4E (0.44) | RPA1ALDH1A1KDM4EMEN1POLB | |
| SCHEMBL6415701 | 0.83 | CSNK2A1 (0.45) | CSNK2A1CSNK2A2CSNK2BPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |