Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205219 | 0.93 | CHRM3 (0.67) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6449681 | 0.90 | CHRM3 (0.60) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6450687 | 0.90 | CHRM3 (0.60) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6417424 | 0.89 | CHRM3 (0.58) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6450680 | 0.88 | CHRM3 (0.55) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6453563 | 0.88 | CHRM3 (0.57) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6416944 | 0.88 | CHRM3 (0.57) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6415502 | 0.88 | CHRM3 (0.57) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6449920 | 0.88 | CHRM3 (0.57) | CHRM3CHRM1CHRM2HDAC2HDAC3 | |
| Trifluoroacetic Acid SCHEMBL6420363 | 0.87 | CHRM3 (0.56) | CHRM3CHRM1CHRM2HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277676-A1 | M3muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277676-A1 | M3muscarinic acetylcholine receptor antagonists | CHRM3, CHRM2, CHRM5 | CHRM3 1/4885CHRM1 8/4885CHRM2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.