Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415498 | 1.00 | MEN1 (0.52) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6416359 | 0.84 | MEN1 (0.58) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6416365 | 0.84 | MEN1 (0.58) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6415831 | 0.84 | MEN1 (0.51) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6415828 | 0.84 | MEN1 (0.51) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6415118 | 0.83 | MEN1 (0.60) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6415113 | 0.83 | MEN1 (0.60) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6423100 | 0.83 | KDM4E (0.62) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6423093 | 0.83 | KDM4E (0.62) | MEN1KMT2AUSP2POLBRAB9A | |
| SCHEMBL6416910 | 0.78 | MEN1 (0.69) | MEN1KMT2AUSP2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861419-B2 | Substituted 1, 4-thiazepine and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2005-03-01 | — | — | US | disclosed |