Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.90 |
| ▸ | EGFR | P00533 | 1/20 | 0.85 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.80 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.80 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.80 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.80 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.80 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.80 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.80 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.80 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.80 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.80 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.80 |
| ▸ | MMP1 | P03956 | 2/20 | 0.71 |
| ▸ | MMP2 | P08253 | 2/20 | 0.71 |
| ▸ | MMP9 | P14780 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415859 | 1.00 | KMT2A (0.90) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL25510255 | 1.00 | KMT2A (0.90) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL3208177 | 0.98 | KMT2A (0.93) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL25193280 | 0.95 | KMT2A (1.00) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL27093047 | 0.94 | KMT2A (0.79) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL27093062 | 0.94 | KMT2A (0.79) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL27093034 | 0.94 | KMT2A (0.79) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL25214026 | 0.92 | KMT2A (0.77) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL25184085 | 0.92 | KMT2A (0.77) | KMT2AEGFRHDAC3HDAC4HDAC1 | |
| SCHEMBL25264834 | 0.92 | KMT2A (0.77) | KMT2AEGFRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12128015-B2 | APE/REF1 inhibitors for the treatment of cancer | CHAPMAN UNIVERSITY (US) | 2024-10-29 | — | — | US | disclosed |
| US-20230157978-A1 | APE/REF1 INHIBITORS FOR THE TREATMENT OF CANCER | CHAPMAN UNIVERSITY | 2023-05-25 | — | — | US | disclosed |
| US-10030176-B2 | Electrically conductive adhesives comprising fluoroelastomers | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-07-24 | — | — | US | disclosed |
| EP-1235107-B1 | Photopolymerizable composition | FUJIFILM CORP (JP) | 2016-11-09 | — | — | EP | disclosed |
| US-20150353779-A1 | ELECTRICALLY CONDUCTIVE ADHESIVES COMPRISING FLUOROELASTOMERS | SOLAR PASTE, LLC | 2015-12-10 | — | — | US | disclosed |
| WO-2014110238-A1 | ELECTRICALLY CONDUCTIVE ADHESIVES COMPRISING FLUOROELASTOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-17 | — | — | WO | disclosed |
| US-6838222-B2 | Recording negatives; lithography printing plates; mixture of addiiton polymer and binder | FUJI PHOTO FILM CO., LTD. (JP) | 2005-01-04 | — | — | US | disclosed |
| US-20020160295-A1 | Recording negatives; lithography printing plates; mixture of addiiton polymer and binder | FUJIFILM CORPORATION (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1235107-A1 | Photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 2002-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230157978-A1 | APE/REF1 INHIBITORS FOR THE TREATMENT OF CANCER | APEX1, AP1G1, AP1M1 | KMT2A 1945/4885EGFR 2189/4885HDAC3 2293/4885 |
| US-12128015-B2 | APE/REF1 inhibitors for the treatment of cancer | APEX1, AP1G1, AP1M1 | KMT2A 1945/4885EGFR 2189/4885HDAC3 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.