SCHEMBL641623

SCHEMBL641623

COC(=O)C=Cc1ccc(OCCO)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
TYR P14679 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58
FDPS P14324 1/20 0.54
GSK3B P49841 1/20 0.53
PTPN1 P18031 1/20 0.51
KDM4E B2RXH2 1/20 0.51
MAPT P10636 1/20 0.51
TTR P02766 1/20 0.50
APP P05067 1/20 0.50
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LMNA P02545 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
ABCG2 Q9UNQ0 2/20 0.48
PPARA Q07869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL641622 1.00 CA12 (0.58) CA12CA1CA2TYRCA7
SCHEMBL17061344 0.93 GAA (0.56) CA12CA1CA2TYRCA7
SCHEMBL17061342 0.93 GAA (0.56) CA12CA1CA2TYRCA7
SCHEMBL14634380 0.92 CA12 (0.57) CA12CA1CA2TYRCA7
SCHEMBL13063554 0.92 CA12 (0.57) CA12CA1CA2TYRCA7
SCHEMBL25444572 0.91 CA12 (0.53) CA12CA1CA2TYRCA7
SCHEMBL14634977 0.91 CA12 (0.55) CA12CA1CA2TYRCA7
SCHEMBL14634976 0.91 CA12 (0.55) CA12CA1CA2TYRCA7
SCHEMBL2223046 0.90 CA12 (0.54) CA12CA1CA2TYRCA7
SCHEMBL14634415 0.90 CA12 (0.54) CA12CA1CA2TYRCA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025088969-A1 COMPOSITION FOR FORMING CURED FILM, CURED FILM, ALIGNMENT MATERIAL, AND RETARDATION MATERIAL 日産化学株式会社 2025-05-01 WO disclosed
WO-2025023309-A1 COMPOSITION FOR FORMING CURED FILM, ALIGNMENT MATERIAL, AND PHASE-DIFFERENCE MATERIAL 日産化学株式会社 2025-01-30 WO disclosed
WO-2023204281-A1 RESIN COMPOSITION FOR THERMOSETTING PHOTO-ALIGNMENT FILMS 日産化学株式会社 2023-10-26 WO disclosed
WO-2023204280-A1 CURED FILM-FORMING COMPOSITION, ALIGNMENT MATERIAL, AND RETARDATION MATERIAL 日産化学株式会社 2023-10-26 WO disclosed
CN-114746512-B Composition for forming cured film, alignment material, and retardation material 日产化学株式会社 2023-09-22 CN disclosed
WO-2023157934-A1 RESIN COMPOSITION FOR THERMOSETTING PHOTO-ALIGNMENT FILMS 日産化学株式会社 2023-08-24 WO disclosed
CN-112384834-B Cured film, alignment material, and retardation material 日产化学株式会社 2023-08-11 CN disclosed
CN-115975155-A Composition for forming cured film for alignment material, and retardation material 日产化学株式会社 2023-04-18 CN disclosed
CN-114746512-A Composition for forming cured film, alignment material, and phase difference material 日产化学株式会社 2022-07-12 CN disclosed
CN-110408159-B Composition for forming cured film, alignment material, and phase difference material 日产化学工业株式会社 2022-02-08 CN disclosed
US-20080139590-A1 QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY CURIS, INC. 2008-06-12 US disclosed
WO-2008033749-A2 QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY CURIS, INC. (US) 2008-03-20 WO disclosed
WO-2008033747-A2 MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS CURIS, INC. (US) 2008-03-20 WO disclosed
US-6833421-B1 Compound ROLIC AG (CH) 2004-12-21 US disclosed
EP-1200494-B1 COMPOUND ROLIC AG (CH) 2004-08-18 EP disclosed
EP-1200494-A1 COMPOUND Rolic AG (CH) 2002-05-02 EP disclosed
WO-2001007495-A1 COMPOUND ROLIC AG (CH) 2001-02-01 WO disclosed
EP-0600064-A1 OPTICAL NON-LINEAR POLYMERS F. HOFFMANN-LA ROCHE AG (CH) 1994-06-08 EP disclosed
WO-1994000797-A1 OPTICAL NON-LINEAR POLYMERS F. HOFFMANN-LA ROCHE AG (CH) 1994-01-06 WO disclosed
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139590-A1 QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY EGFR, HDAC1, HDAC6 CA12 2391/4885CA1 2998/4885CA2 2379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.