Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 20/20 | 0.62 |
| ▸ | INSR | P06213 | 10/20 | 0.62 |
| ▸ | TXK | P42681 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6416912 | 0.92 | ITK (0.72) | ITKINSRTXK | |
| SCHEMBL6416240 | 0.88 | ITK (0.61) | ITKINSRTXK | |
| SCHEMBL6417114 | 0.86 | ITK (0.59) | ITKINSRTXK | |
| SCHEMBL6414836 | 0.86 | ITK (0.59) | ITKINSRTXK | |
| SCHEMBL6273363 | 0.84 | ITK (0.56) | ITKINSRTXK | |
| SCHEMBL6277033 | 0.83 | ITK (0.54) | ITKINSRTXK | |
| SCHEMBL6415040 | 0.83 | ITK (0.54) | ITKINSRTXK | |
| SCHEMBL6419531 | 0.83 | ITK (0.57) | ITKINSRTXK | |
| SCHEMBL6272966 | 0.83 | ITK (0.54) | ITKINSRTXK | |
| SCHEMBL6272351 | 0.83 | ITK (0.54) | ITKINSRTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | TEC, ITK, TXK | ITK 2/4885INSR 910/4885TXK 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.