SCHEMBL6417657

SCHEMBL6417657

[CH2]Cc1ccc(Cl)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.59
CYP1A2 P05177 4/20 0.59
GPR84 Q9NQS5 4/20 0.41
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
NR4A2 P43354 1/20 0.37
LMNA P02545 3/20 0.34
TSHR P16473 3/20 0.34
HPGD P15428 2/20 0.33
PNMT P11086 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
IDO1 P14902 1/20 0.33
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15351192 0.86 CYP1A2 (0.59) CYP2A6CYP1A2NR4A2LMNATSHR
SCHEMBL7915217 0.79 CYP2A6 (0.62) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL5372145 0.79 CYP2A6 (0.62) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL8824635 0.77 CYP2A6 (0.59) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL15345474 0.77 CYP2A6 (0.59) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL14444102 0.77 CYP1A2 (0.59) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL10409318 0.77 CYP2A6 (0.59) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL15352053 0.77 CYP1A2 (0.59) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL8851365 0.77 CYP1A2 (0.59) CYP2A6CYP1A2GPR84KMT2AATM
SCHEMBL29494605 0.77 CYP2A6 (1.00) CYP2A6CYP1A2KMT2AATMNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1180765-B1 Optical recording medium and porphycene compound MITSUI CHEMICALS INC (JP) 2005-04-06 EP disclosed
EP-1180765-A1 Optical recording medium and porphycene compound Mitsui Chemicals, Inc. (JP) 2002-02-20 EP disclosed
US-4053478-A ARTERIOSCLEROSIS, THROMBOSIS, HYPERTENSION YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) 1977-10-11 US disclosed
US-4012412-A USEFUL IN THE TREATMENT OF HYPERTENSION, ARTERIOSCLEROSIS, AND THROMBOSIS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) 1977-03-15 US disclosed