Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | ARNT | P27540 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6421068 | 0.99 | MAPT (0.49) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3051396 | 0.92 | TP53 (0.55) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL6416881 | 0.87 | MAPT (0.51) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| Hydrochloric Acid SCHEMBL6413527 | 0.86 | MAPT (0.50) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3059036 | 0.85 | TP53 (0.53) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3055646 | 0.84 | TP53 (0.58) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3058473 | 0.82 | MAPT (0.48) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3055713 | 0.82 | MAPT (0.50) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| SCHEMBL3052187 | 0.82 | HTT (0.57) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| Ammonia Solution, Strong SCHEMBL4262270 | 0.81 | MAPT (0.53) | MAPTSMN1; SMN2TP53CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |