Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL6418315

C#CCCC(=O)O.C#CCCC(=O)O.OCCOCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
CYP2D6 P10635 2/20 0.47
MAPT P10636 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MAPK1 P28482 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CAMK2A Q9UQM7 1/20 0.36
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
LMNA P02545 2/20 0.32
NFKB1 P19838 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL6420421 0.84 CYP2D6 (0.56) TSHRCYP2D6MAPTCYP1A2CYP2C9
SCHEMBL8803 0.82
Di(Hydroxyethyl)Ether SCHEMBL6422932 0.80 TSHR (0.48) TSHRCYP2D6MAPTCYP1A2CYP2C9
Ammonia Solution, Strong SCHEMBL15140025 0.79
Hydrochloric Acid SCHEMBL2121345 0.79
Succinic Acid SCHEMBL1986734 0.79 TSHR (0.59) TSHRHSD17B10MAPK1MEN1KMT2A
SCHEMBL9256056 0.78 CYP2D6 (0.50) TSHRCYP2D6MAPTCYP1A2CYP2C9
SCHEMBL16561495 0.77
Tetraethylene Glycol SCHEMBL15049107 0.77 MEN1 (0.61) TSHRMAPTHSD17B10MAPK1MEN1
Succinic Acid SCHEMBL10943498 0.77 TSHR (0.56) TSHRHSD17B10MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050281968-A1 Energetic structural material ALLIANT TECHSYSTEMS INC. (US) 2005-12-22 US claimed
US-20050281968-A1 Energetic structural material ALLIANT TECHSYSTEMS INC. (US) 2005-12-22 US disclosed