Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046526 | 0.82 | P2RY14 (0.41) | P2RY14PTPN1PTGER1DHODHRXRA | |
| SCHEMBL5046531 | 0.82 | P2RY14 (0.41) | P2RY14PTPN1PTGER1DHODHRXRA | |
| SCHEMBL6423613 | 0.75 | HPGD (0.49) | PTPN1PTGER1KDM4E | |
| SCHEMBL6422110 | 0.74 | MAOB (0.46) | P2RY14KDM4ERXRARXRBRXRG | |
| SCHEMBL6422106 | 0.74 | MAOB (0.46) | P2RY14KDM4ERXRARXRBRXRG | |
| SCHEMBL5049355 | 0.71 | PTPN1 (0.38) | PTPN1DHODH | |
| SCHEMBL5049354 | 0.71 | PTPN1 (0.38) | PTPN1DHODH | |
| SCHEMBL6423841 | 0.68 | ERN1 (0.41) | PTPN1 | |
| SCHEMBL8797209 | 0.65 | PTGER1 (0.55) | P2RY14PTGER1PTGER4RXRARXRB | |
| SCHEMBL6419672 | 0.64 | MAOB (0.47) | P2RY14RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513793-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003101928-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2003-12-11 | — | — | WO | disclosed |