⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728794 | 0.82 | KDM4E (0.52) | — | |
| SCHEMBL1178754 | 0.82 | KDM4E (0.50) | — | |
| Hydrochloric Acid SCHEMBL31656522 | 0.80 | KDM4E (0.54) | — | |
| Hydrochloric Acid SCHEMBL4838526 | 0.80 | KDM4E (0.54) | — | |
| SCHEMBL2002016 | 0.80 | HRH1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL1954121 | 0.80 | KDM4E (0.54) | — | |
| SCHEMBL4190714 | 0.80 | KDM4E (0.50) | — | |
| SCHEMBL15617823 | 0.77 | NPC1 (0.43) | — | |
| SCHEMBL15911434 | 0.77 | NPC1 (0.43) | — | |
| SCHEMBL29263736 | 0.77 | HRH1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119185-B2 | Protective material comprising reversible and irreversible photochemical functional constituents | Philips-Universitaet Marburg (DE) | 2012-02-21 | — | — | US | claimed |
| US-20090133196-A1 | Protective Material Comprising Reversible and Irreversible Photochemical Functional Constituents | Philips-Universitaet Marburg (DE) | 2009-05-28 | — | — | US | claimed |
| EP-1767988-A1 | Security material with reversible and irreversible photochemical components and coating methods | AgfaPhoto GmbH (DE) | 2007-03-28 | — | — | EP | claimed |
| WO-2006103238-A1 | PROTECTIVE MATERIAL COMPRISING REVERSIBLE AND IRREVERSIBLE PHOTOCHEMICAL FUNCTIONAL CONSTITUENTS, AND COATING METHOD | AGFA-GEVAERT AG (DE) | 2006-10-05 | — | — | WO | claimed |
| US-4914213-A | Indole derivatives and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-03 | — | — | US | claimed |
| US-4707553-A | Indole derivatives and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1987-11-17 | — | — | US | claimed |
| EP-2953948-B1 | FLUORINATED INTEGRIN ANTAGONISTS | SCIFLUOR LIFE SCIENCES INC (US) | 2017-09-27 | — | — | EP | disclosed |
| WO-2014124302-A1 | FLUORINATED INTEGRIN ANTAGONISTS | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-08-14 | — | — | WO | disclosed |
| US-8119185-B2 | Protective material comprising reversible and irreversible photochemical functional constituents | Philips-Universitaet Marburg (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090133196-A1 | Protective Material Comprising Reversible and Irreversible Photochemical Functional Constituents | Philips-Universitaet Marburg (DE) | 2009-05-28 | — | — | US | disclosed |
| CN-100376574-C | Preparation process of taytrolazole | UNIV ZHEJIANG (CN) | 2008-03-26 | — | — | CN | disclosed |
| EP-1767988-A1 | Security material with reversible and irreversible photochemical components and coating methods | AgfaPhoto GmbH (DE) | 2007-03-28 | — | — | EP | disclosed |
| CN-1861600-A | Preparation process of taytrolazole | UNIV ZHEJIANG (CN) | 2006-11-15 | — | — | CN | disclosed |
| US-6030976-A | SELECTIVE AFFINITY TO 5HT-6 RECEPTORS; CENTRAL NERVOUS SYSTEM DISORDERS; ALZHEIMER'S DISEASE, PSYCHOSES, SCHIZOPHRENIA, MANIC DEPRESSIONS, MEMORY DISORDERS, PARKINSON'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS AND HUNTINGTON'S DISEASE | HOFFMAN-LA ROCHE INC. (US) | 2000-02-29 | — | — | US | disclosed |
| US-5998665-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-12-07 | — | — | US | disclosed |
| US-5939451-A | INDOL-4-YL-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-17 | — | — | US | disclosed |
| US-5932599-A | 4-AMINO-N-(PYRIDINYL-4-YL)-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0815861-A1 | Sulphonamides and their use | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| US-4914213-A | Indole derivatives and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4707553-A | Indole derivatives and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1987-11-17 | — | — | US | disclosed |