SCHEMBL6420046

SCHEMBL6420046

CC(=O)OC(C)(OC(C)=O)[SiH2]CCCOCC1CO1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPK1 P28482 1/20 0.39
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6419951 0.83 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28487067 0.82 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL6420507 0.81 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL6420575 0.79 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL6423192 0.79 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL6422965 0.78 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL13864102 0.78 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28041186 0.76 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL13864091 0.75 TSHR (0.49) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4802643 0.74 TSHR (0.49) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6953754-B2 Functional device and method of manufacturing the same SONY CORPORATION (JP) 2005-10-11 US disclosed
US-20040157470-A1 Functional device and production method therefor SONY CORPORATION (JP) 2004-08-12 US disclosed