Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271298 | 0.87 | RPS6KA5 (0.45) | KDM4ERAD52HTTTLR8BACE1 | |
| SCHEMBL21310819 | 0.87 | TLR8 (0.58) | KDM4ERAD52HTTTLR8BACE1 | |
| SCHEMBL21311070 | 0.85 | TLR8 (0.41) | KDM4ERAD52HTTTLR8BACE1 | |
| SCHEMBL21310822 | 0.85 | BACE1 (0.41) | HTTTLR8BACE1NUDT1CNR2 | |
| SCHEMBL21310816 | 0.85 | BACE1 (0.60) | HTTTLR8BACE1NUDT1ALDH1A1 | |
| SCHEMBL21310933 | 0.85 | RPS6KA5 (0.44) | HTTTLR8BACE1NUDT1CYP1A2 | |
| SCHEMBL21310846 | 0.84 | RPS6KA5 (0.47) | KDM4EHTTTLR8BACE1NUDT1 | |
| SCHEMBL21310820 | 0.84 | TLR8 (0.43) | KDM4ERAD52HTTTLR8BACE1 | |
| SCHEMBL21310890 | 0.83 | BACE1 (0.39) | KDM4ERAD52HTTTLR8BACE1 | |
| SCHEMBL21310821 | 0.83 | JAK2 (0.41) | KDM4ERAD52HTTTLR8BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | TEC, ITK, TXK | KDM4E 2880/4885RAD52 2712/4885HTT 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.