Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 15/20 | 0.56 |
| ▸ | INSR | P06213 | 11/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421021 | 0.85 | ITK (0.53) | ITKINSRHDAC6 | |
| SCHEMBL6420992 | 0.81 | ITK (0.55) | ITKINSR | |
| SCHEMBL6420438 | 0.81 | ITK (0.55) | ITKINSR | |
| SCHEMBL6274629 | 0.81 | ITK (0.55) | ITKINSR | |
| SCHEMBL6273956 | 0.80 | ITK (0.55) | ITKINSRHDAC6HDAC1 | |
| SCHEMBL6273767 | 0.80 | ITK (0.42) | ITKINSRHDAC1 | |
| SCHEMBL6420350 | 0.80 | ITK (0.50) | ITKINSR | |
| SCHEMBL6273963 | 0.78 | ITK (0.49) | ITKINSRHDAC6 | |
| SCHEMBL6418924 | 0.78 | ITK (0.46) | ITKINSRHDAC6HDAC1 | |
| SCHEMBL6271293 | 0.77 | JAK2 (0.45) | ITKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | TEC, ITK, TXK | ITK 2/4885INSR 910/4885HDAC6 894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.