Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
| ▸ | PPARG | P37231 | 14/20 | 0.55 |
| ▸ | PPARD | Q03181 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421706 | 0.96 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL6418466 | 0.93 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL6420564 | 0.92 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL6420459 | 0.86 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6422692 | 0.83 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL5386198 | 0.81 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL5380615 | 0.81 | PPARA (0.82) | PPARAPPARGPPARD | |
| SCHEMBL5386183 | 0.81 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL2554435 | 0.79 | PPARA (0.52) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL4758109 | 0.79 | PPARA (0.75) | PPARAPPARGPPARDFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972294-B1 | Compounds, their preparation and use | NOVO NORDISK, A/S (DK) | 2005-12-06 | — | — | US | claimed |
| JP-2002542218-A | — | — | 2002-12-10 | — | — | JP | claimed |
| EP-1171414-A1 | COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-16 | — | — | EP | claimed |
| WO-2000063153-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | claimed |
| US-6972294-B1 | Compounds, their preparation and use | NOVO NORDISK, A/S (DK) | 2005-12-06 | — | — | US | disclosed |
| EP-1171414-A1 | COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063153-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |