SCHEMBL6421692

SCHEMBL6421692

CCO[C@@H](Cc1ccc(OC/C=C(/c2ccccc2)c2ccc(-c3ccccc3)cc2)cc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 1.00
PPARA Q07869 20/20 1.00
PPARG P37231 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6421690 1.00 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL6423352 1.00 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL6423350 1.00 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL6435562 1.00 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL6421694 1.00 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL6420473 0.99 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL7574400 0.99 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL6422446 0.94 PPARD (1.00) PPARDPPARAPPARG
SCHEMBL6419903 0.92 PPARD (0.85) PPARDPPARAPPARG
SCHEMBL6419907 0.92 PPARD (0.85) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6972294-B1 Compounds, their preparation and use NOVO NORDISK, A/S (DK) 2005-12-06 US claimed
JP-2002542218-A 2002-12-10 JP claimed
EP-1171414-A1 COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2002-01-16 EP claimed
WO-2000063153-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-10-26 WO claimed
US-6972294-B1 Compounds, their preparation and use NOVO NORDISK, A/S (DK) 2005-12-06 US disclosed
EP-1171414-A1 COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2002-01-16 EP disclosed
WO-2000063153-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-10-26 WO disclosed