SCHEMBL6421786

SCHEMBL6421786

CCCCOC(=O)/C=C\C(=O)O[SiH2]CCCC

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.69
HCAR2 Q8TDS4 5/20 0.61
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
ALDH1A1 P00352 1/20 0.42
APP P05067 5/20 0.42
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6421793 1.00 ATM (0.69) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2353799 0.90 HCAR2 (0.63) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2353792 0.90 HCAR2 (0.63) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2356403 0.90 HCAR2 (0.63) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2356398 0.90 HCAR2 (0.63) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL6685300 0.90 HCAR2 (0.63) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2357459 0.90 HCAR2 (0.63) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28313586 0.88 HCAR2 (0.62) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL6554016 0.87 ATM (0.61) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL6556024 0.87 ATM (0.61) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-3700985-A1 SELF-POLISHING ANTIFOULING COATING COMPOSITION COMPRISING ALKOXYSILANE Hempel A/S (DK) 2020-09-02 EP disclosed