⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984211 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL11155064 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL65782 | 0.97 | — | — | |
| SCHEMBL984562 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL9146095 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL11350530 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL984213 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL980873 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL545411 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL8915172 | 0.97 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7014 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215729-B | Preparation method of polyester-grade coal-based ethylene glycol | 中国石油化工股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-115216342-B | Preparation method of polyester-grade coal-based ethylene glycol | 中国石油化工股份有限公司 | 2023-09-01 | — | — | CN | claimed |
| WO-2023122724-A1 | IMPROVED SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES | P2 SCIENCE, INC. (US) | 2023-06-29 | — | — | WO | claimed |
| EP-4178937-A1 | VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME | Amyris, Inc. (US) | 2023-05-17 | — | — | EP | claimed |
| CN-115215729-A | Preparation method of polyester-grade coal-based ethylene glycol | 中国石油化工股份有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-115216342-A | Preparation method of polyester-grade coal-based ethylene glycol | 中国石油化工股份有限公司 | 2022-10-21 | — | — | CN | claimed |
| WO-2022011031-A1 | VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME | Amyris, Inc. (US) | 2022-01-13 | — | — | WO | claimed |
| EP-3492451-B1 | PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-11-03 | — | — | EP | claimed |
| CN-110003114-A | Diarylhydantoin compounds | 加利福尼亚大学董事会 | 2019-07-12 | — | — | CN | claimed |
| EP-3216784-B1 | PROCESS FOR THE PREPARATION OF HISTAMINE H3 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-12-26 | — | — | EP | claimed |
| CN-1035824-A | The preparation method of 1-alkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-27 | — | — | CN | claimed |
| CN-1035289-A | The preparation method of 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1989-09-06 | — | — | CN | claimed |
| EP-0286926-A2 | Semi-synthetic rhodomycins, method for their preparation and their use as cytostatics | BEHRINGWERKE Aktiengesellschaft (DE) | 1988-10-19 | — | — | EP | claimed |
| US-4758373-A | Carbocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-19 | — | — | US | claimed |
| US-4675186-A | 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives | PFIZER INC. (US) | 1987-06-23 | — | — | US | claimed |
| CN-86102736-A | The preparation method and the application thereof of 6-(1-acyl group-1-methylol) penicillanic acid derivative | — | 1986-10-15 | — | — | CN | claimed |
| US-4464237-A | ELECTROLYZING AZETIDINONE DERIVATIVES, CEPHALOSPORIN OR PENICILLIN INTERMEDIATES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1984-08-07 | — | — | US | claimed |
| US-4015012-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | claimed |
| US-3970699-A | 4-Acylaminophenylacetamidines and a method for their preparation | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | claimed |
| US-3970692-A | Process for the preparation of prostaglandin F2.sub.α and the analogs thereof | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | claimed |