Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229219 | 1.00 | ESR1 (0.56) | ESR1ESR2CYP26A1DRD2DRD1 | |
| SCHEMBL227960 | 0.92 | ESR1 (0.68) | ESR1ESR2CYP26A1DRD2DRD3 | |
| SCHEMBL229161 | 0.91 | ESR1 (0.56) | ESR1ESR2CYP26A1DRD2DRD1 | |
| SCHEMBL12570022 | 0.90 | ESR1 (0.48) | ESR1ESR2CYP26A1DRD2DRD1 | |
| SCHEMBL228552 | 0.86 | ESR1 (0.59) | ESR1ESR2CYP26A1DRD2MEN1 | |
| SCHEMBL229917 | 0.86 | ESR1 (0.59) | ESR1ESR2CYP26A1DRD2MEN1 | |
| SCHEMBL228882 | 0.86 | ESR1 (0.59) | ESR1ESR2CYP26A1DRD2DRD1 | |
| SCHEMBL229963 | 0.86 | ESR1 (0.59) | ESR1ESR2CYP26A1DRD2DRD1 | |
| SCHEMBL226217 | 0.85 | ESR1 (0.58) | ESR1ESR2CYP26A1DRD2DRD1 | |
| SCHEMBL226432 | 0.85 | ESR1 (0.56) | ESR1ESR2CYP26A1DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |