Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335849 | 0.84 | MAOB (0.55) | MAOBLTA4HMAOAHDAC1HDAC2 | |
| SCHEMBL4337731 | 0.84 | MAOB (0.55) | MAOBLTA4HMAOAHDAC1HDAC2 | |
| SCHEMBL4339933 | 0.83 | MAOB (0.55) | MAOBLTA4HMAOAHDAC1HDAC2 | |
| SCHEMBL4342930 | 0.82 | MAOB (0.53) | MAOBLTA4HMAOAHDAC1HDAC2 | |
| SCHEMBL3504655 | 0.82 | MAOB (0.54) | MAOBMAOAHDAC1HDAC2POLB | |
| Hydrochloric Acid SCHEMBL5617603 | 0.81 | MAOB (0.52) | MAOBLTA4HMAOAHDAC1HDAC2 | |
| SCHEMBL3506683 | 0.81 | MAOB (0.56) | MAOBTP53MAOAHDAC1HDAC2 | |
| SCHEMBL4340508 | 0.80 | MAOB (0.53) | MAOBMAOAHDAC1HDAC2POLB | |
| SCHEMBL1578374 | 0.79 | MAOB (0.57) | MAOBMAOAHDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL5090204 | 0.79 | HDAC1 (0.53) | MAOBMAOAHDAC1HDAC2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511718-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003099763-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-12-04 | — | — | WO | disclosed |