SCHEMBL6422261

SCHEMBL6422261

CCCCCCc1ccc(-c2ccc(-c3ccc(-c4ccc(-c5ccc(CCCCCC)cc5)s4)s3)s2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.53
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
LMNA P02545 1/20 0.53
SHBG P04278 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53
HIF1A Q16665 1/20 0.53
TST Q16762 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449126 1.00 HSD17B10 (0.53) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL1231095 1.00 HSD17B10 (0.53) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL6421748 1.00 HSD17B10 (0.53) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL14703081 0.98 HSD17B10 (0.56) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL6418801 0.98 HSD17B10 (0.55) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL2466020 0.98 HSD17B10 (0.55) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL6418550 0.96 HSD17B10 (0.57) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL20814263 0.91 KDM4E (0.49) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL13480622 0.91 KDM4E (0.46) HSD17B10KDM4EALDH1A1ESR1ADRA2A
SCHEMBL15070058 0.91 KDM4E (0.46) HSD17B10KDM4EALDH1A1ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450723-B2 Apparatus having an aromatic dielectric and an aromatic organic semiconductor including an alkyl chain ALCATEL LUCENT (FR) 2013-05-28 US claimed
US-20050093031-A1 Devices having large organic semiconductor crystals and methods of making the same LUCENT TECHNOLOGIES, INC. (US) 2005-05-05 US claimed
US-8450723-B2 Apparatus having an aromatic dielectric and an aromatic organic semiconductor including an alkyl chain ALCATEL LUCENT (FR) 2013-05-28 US disclosed
US-20050093031-A1 Devices having large organic semiconductor crystals and methods of making the same LUCENT TECHNOLOGIES, INC. (US) 2005-05-05 US disclosed