Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422298 | 1.00 | KMT2A (0.53) | KMT2ATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL6423082 | 0.92 | MEN1 (0.51) | KMT2ATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL6423084 | 0.92 | MEN1 (0.51) | KMT2ATSHRLMNAMEN1CYP1A2 | |
| SCHEMBL6378318 | 0.87 | MEN1 (0.52) | KMT2ALMNAMEN1CYP1A2MAPK1 | |
| SCHEMBL6378002 | 0.87 | MEN1 (0.52) | KMT2ALMNAMEN1CYP1A2MAPK1 | |
| SCHEMBL6378003 | 0.87 | MEN1 (0.52) | KMT2ALMNAMEN1CYP1A2MAPK1 | |
| SCHEMBL6427184 | 0.87 | MEN1 (0.56) | KMT2ALMNAMEN1CYP1A2MAPK1 | |
| SCHEMBL6427180 | 0.87 | MEN1 (0.56) | KMT2ALMNAMEN1CYP1A2MAPK1 | |
| SCHEMBL6382966 | 0.86 | MEN1 (0.51) | KMT2ALMNAMEN1CYP1A2MAPK1 | |
| SCHEMBL8958950 | 0.86 | MEN1 (0.58) | KMT2ALMNAMEN1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929521-B1 | NMDA (N-METHYL-D-ASPARTATE) ANTAGONISTS | AVENTIS PHARMA INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-0929521-A1 | NMDA (N-METHYL-D-ASPARTATE) ANTAGONISTS | HOECHST MARION ROUSSEL, INC. (US) | 1999-07-21 | — | — | EP | disclosed |
| US-5922752-A | NMDA (n-methyl-d-aspartate) antagonists | HOECHST MARION ROUSSELL, INC. (US) | 1999-07-13 | — | — | US | disclosed |
| WO-1998014427-A1 | NMDA (N-METHYL-D-ASPARTATE) ANTAGONISTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-04-09 | — | — | WO | disclosed |