SCHEMBL642253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18010031	0.91	AKR1C4 (0.43)	CA12CA1CA2CA7CA9
	SCHEMBL642424	0.84	CA12 (0.56)	CA12CA1CA2CA7CA9
	SCHEMBL5932063	0.81	GAA (0.45)	KDM4EGAAMAOBHPGDMAPT
	SCHEMBL713400	0.80	CA12 (0.63)	CA12CA1CA2CA7CA9
	SCHEMBL2350986	0.78	CA1 (0.61)	CA12CA1CA2CA7CA9
	SCHEMBL2313483	0.78	MAPT (0.64)	CA1CA2LMNAGAATDP1
	SCHEMBL643593	0.78	CA12 (0.56)	CA12CA1CA2CA7CA9
	SCHEMBL642561	0.78	MAOB (0.52)	KDM4ETDP1MAOBHPGDCYSLTR1
	SCHEMBL2650746	0.77	CA12 (0.59)	CA12CA1CA2CA7CA9
	SCHEMBL4585878	0.77	CA12 (0.59)	CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.