Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423156 | 0.90 | TNFRSF1A (0.41) | TNFRSF1AMAOBCYP3A4MAPTTP53 | |
| SCHEMBL1406757 | 0.89 | MAOB (0.48) | TNFRSF1AMAOBCYP3A4MAPTTP53 | |
| SCHEMBL1406578 | 0.89 | MAOB (0.48) | TNFRSF1AMAOBCYP3A4MAPTTP53 | |
| SCHEMBL6423154 | 0.87 | MAOB (0.40) | TNFRSF1AMAOBCYP3A4MAPTABCG2 | |
| SCHEMBL1406562 | 0.83 | PTGER1 (0.44) | SMN1; SMN2AKR1C3PTGER1RXRARXRB | |
| SCHEMBL1406560 | 0.83 | PTGER1 (0.44) | SMN1; SMN2AKR1C3PTGER1RXRARXRB | |
| SCHEMBL1406756 | 0.82 | TP53 (0.53) | TNFRSF1AMAOBCYP3A4MAPTTP53 | |
| SCHEMBL1406530 | 0.82 | TP53 (0.53) | TNFRSF1AMAOBCYP3A4MAPTTP53 | |
| SCHEMBL6454591 | 0.80 | PTGER1 (0.37) | TNFRSF1AMAOBABCG2AKR1C3PTGER1 | |
| SCHEMBL6454585 | 0.80 | PTGER1 (0.37) | TNFRSF1AMAOBABCG2AKR1C3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513793-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-03-16 | — | — | EP | claimed |
| WO-2003101928-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2003-12-11 | — | — | WO | claimed |