Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664136 | 0.86 | TSHR (0.53) | KMT2AMEN1CYP3A4TSHRALDH1A1 | |
| SCHEMBL9422015 | 0.85 | CYP3A4 (0.67) | KMT2AMEN1CYP3A4TSHRCYP2D6 | |
| SCHEMBL27952157 | 0.85 | CYP3A4 (0.45) | KMT2AMEN1CYP3A4TSHRALDH1A1 | |
| SCHEMBL27851179 | 0.84 | MEN1 (0.50) | KMT2AMEN1CYP3A4TSHRCYP2D6 | |
| SCHEMBL17788974 | 0.82 | KMT2A (0.57) | KMT2AMEN1CYP3A4TSHRCYP2D6 | |
| SCHEMBL30968707 | 0.82 | TSHR (0.68) | KMT2AMEN1CYP3A4TSHRCYP2D6 | |
| SCHEMBL574192 | 0.82 | TSHR (0.68) | KMT2AMEN1CYP3A4TSHRCYP2D6 | |
| SCHEMBL3487724 | 0.81 | CA12 (0.47) | KMT2AMEN1CYP3A4TSHRCYP2D6 | |
| Ammonia Solution, Strong SCHEMBL29087129 | 0.81 | TSHR (0.66) | KMT2AMEN1CYP3A4TSHRCYP2D6 | |
| SCHEMBL998093 | 0.79 | KMT2A (0.55) | KMT2AMEN1CYP3A4TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150275268-A1 | STABILISATION OF BIOLOGICAL SAMPLES | QIAGEN GMBH (DE) | 2015-10-01 | — | — | US | disclosed |
| US-6921633-B2 | Methods and compositions for the preservation of cells, tissues or organs in the vitreous state | BIOLIFE SOLUTIONS INCORPORATED (US) | 2005-07-26 | — | — | US | disclosed |
| US-6310273-B1 | AMPLIFIYING DISEASE RESISTANCE IN PLANTS; TRANSFORMING PLANT, EXPRESS GENE OF INTEREST, MONITOR PLANT FOR RESISTANCE TO DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-10-30 | — | — | US | disclosed |
| WO-2000009664-A9 | INHIBITING APOPTOSIS IN PLANTS USING A CASPASE INHIBITOR | UNIV CALIFORNIA (US) | 2000-09-08 | — | — | WO | disclosed |
| WO-2000009664-A1 | INHIBITING APOPTOSIS IN PLANTS USING A CASPASE INHIBITOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-02-24 | — | — | WO | disclosed |