Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.74 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.74 |
| ▸ | ITGB6 | P18564 | 11/20 | 0.72 |
| ▸ | ITGB8 | P26012 | 11/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421975 | 1.00 | ITGAV (0.74) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6421979 | 1.00 | ITGAV (0.74) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6420972 | 0.85 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6421638 | 0.85 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6421627 | 0.85 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6359531 | 0.85 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6421564 | 0.85 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6421303 | 0.85 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL6106842 | 0.84 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL7318506 | 0.84 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040098-B1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2005-04-27 | — | — | EP | claimed |