⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19168030 | 1.00 | — | — | |
| SCHEMBL1628866 | 1.00 | — | — | |
| SCHEMBL17232123 | 1.00 | — | — | |
| SCHEMBL1628862 | 1.00 | — | — | |
| SCHEMBL561454 | 1.00 | — | — | |
| SCHEMBL19242845 | 0.75 | — | — | |
| SCHEMBL18266878 | 0.73 | — | — | |
| SCHEMBL16176584 | 0.73 | PTPN1 (0.32) | — | |
| SCHEMBL16176240 | 0.73 | PTPN1 (0.32) | — | |
| SCHEMBL16176245 | 0.73 | PTPN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023284-B1 | ANTI-VIRAL PHARMACEUTICAL COMPOSITIONS CONTAINING SATURATED 1,2-DITHIAHETEROCYCLIC COMPOUNDS | US GOV HEALTH & HUMAN SERV (US) | 2005-11-23 | — | — | EP | claimed |
| US-6046228-A | INCLUDE 1,2-DITHIANE AND 1,2 DITHIOLANE COMPOUNDS, THE RING SULFUR ATOMS MAY BE PRESENT IN THE SULFUR OXIDE OR SULFONE STATE, USEFUL FOR INHIBITING RETROVIRUS REPLICATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-04-04 | — | — | US | claimed |
| WO-1998001440-A9 | ANTI-VIRAL PHARMACEUTICAL COMPOSITIONS CONTAINING SATURATED 1,2-DITHIAHETEROCYCLIC COMPOUNDS AND USES THEREOF | — | 1998-07-16 | — | — | WO | claimed |
| US-11723857-B2 | Covalent treatment with thiols of keratin-containing materials | LIVING PROOF, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-10993903-B2 | Covalent treatment with thiols of keratin-containing materials | LIVING PROOF, INC. (US) | 2021-05-04 | — | — | US | disclosed |
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | SABILA BIOSCIENCES LLC (US) | 2020-11-24 | — | — | US | disclosed |
| US-10844038-B2 | 1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions | SABILA BIOSCIENCES LLC (US) | 2020-11-24 | — | — | US | disclosed |
| US-10436798-B2 | Means and methods for diagnosing and monitoring heart failure in a subject | METANOMICS GMBH (DE) | 2019-10-08 | — | — | US | disclosed |
| US-20190254955-A1 | COVALENT TREATMENT WITH THIOLS OF KERATIN-CONTAINING MATERIALS | LIVING PROOF, INC. | 2019-08-22 | — | — | US | disclosed |
| EP-3527990-A1 | USE OF SM_SPHINGOMYELIN (D18:1, C23:1) AS A MARKER FOR HEART FAILURE | metanomics GmbH (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-3190418-B1 | USE OF SM_SPHINGOMYELIN (D18:1, C16:0) AS A MARKER FOR HEART FAILURE | METANOMICS GMBH (DE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2018049127-A1 | 1,2-DITHIOLANE COMPOUNDS USEFUL IN NEUROPROTECTION, AUTOIMMUNE AND CANCER DISEASES AND CONDITIONS | SABILA BIOSCIENCES LLC (US) | 2018-03-15 | — | — | WO | disclosed |
| EP-3190418-A1 | USE OF SM_SPHINGOMYELIN (D18:1, C16:0) AS A MARKER FOR HEART FAILURE | metanomics GmbH (DE) | 2017-07-12 | — | — | EP | disclosed |
| EP-2737321-B1 | MEANS AND METHODS FOR DIAGNOSING AND MONITORING HEART FAILURE IN A SUBJECT | METANOMICS GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-20150160238-A1 | Means and Methods for Diagnosing and Monitoring Heart Failure in a Subject | RUPRECHT-KARLS-UNIVERISTÄT HEIDELBERG (DE) | 2015-06-11 | — | — | US | disclosed |
| EP-2737321-A2 | MEANS AND METHODS FOR DIAGNOSING AND MONITORING HEART FAILURE IN A SUBJECT | Metanomics GmbH (DE) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013014286-A2 | MEANS AND METHODS FOR DIAGNOSING AND MONITORING HEART FAILURE IN A SUBJECT | METANOMICS GMBH (DE) | 2013-01-31 | — | — | WO | disclosed |