SCHEMBL6424182

SCHEMBL6424182

O=C(O)CN1CCN(CC(=O)O)CCN(CP(=O)(O)O)CCN(CP(=O)(O)O)CC1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.47
MAPT P10636 2/20 0.43
SLC6A9 P48067 1/20 0.38
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
BLM P54132 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
S1PR1 P21453 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
ANPEP P15144 1/20 0.31
ERAP2 Q6P179 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5059158 1.00 HSD17B10 (0.47) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL7039511 1.00 HSD17B10 (0.47) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL3974583 1.00 HSD17B10 (0.47) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL27329590 1.00 HSD17B10 (0.47) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL29299517 0.91 HSD17B10 (0.40) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL18537917 0.91 HSD17B10 (0.40) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL18537936 0.91 HSD17B10 (0.40) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL22821626 0.91 HSD17B10 (0.40) HSD17B10MAPTSLC6A9MEN1LMNA
SCHEMBL15831767 0.91 HSD17B10 (0.40) HSD17B10MAPTMEN1TSHRKMT2A
SCHEMBL18537914 0.91 HSD17B10 (0.40) HSD17B10MAPTSLC6A9MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed
WO-2024129600-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-06-20 WO disclosed
WO-2024112612-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-05-30 WO disclosed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 WO disclosed
EP-1047677-B1 Process for the preparation of derivatives of 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid BRACCO SPA (IT) 2005-07-20 EP disclosed
EP-0717639-B1 POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI CHELATOR LLC (US) 2003-04-02 EP disclosed
EP-0717639-A4 POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI CONCAT LTD (US) 1998-04-01 EP disclosed
EP-0717639-A1 POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI CONCAT LTD. (US) 1996-06-26 EP disclosed
US-5409689-A MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms CONCAT, LTD. (US) 1995-04-25 US disclosed
WO-1995005118-A1 POLYAMINO PARAMAGNETIC CHELATES WHICH CONTAIN BOTH PHOSPHONATE AND NON-PHOSPHONATE MOIETIES FOR MRI CONCAT LTD. (US) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R HSD17B10 3848/4885MAPT 2444/4885SLC6A9 2603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.