Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.68 |
| ▸ | HMGCR | P04035 | 7/20 | 0.62 |
| ▸ | SELP | P16109 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453291 | 0.96 | PTPN7 (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL3796753 | 0.96 | PTPN7 (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL2181335 | 0.92 | HMGCR (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL1918073 | 0.92 | HMGCR (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL4225757 | 0.92 | HMGCR (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL2180780 | 0.92 | HMGCR (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL4231623 | 0.92 | HMGCR (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL2201502 | 0.92 | HMGCR (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| SCHEMBL2182049 | 0.92 | HMGCR (0.72) | PTPN7HMGCRSELPRECQLTDP1 | |
| Propylamine SCHEMBL942324 | 0.91 | PTPN7 (0.66) | PTPN7HMGCRSELPRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003085397-A2 | PLURAL INTRINSIC EXPIRATION INITIATION APPLICATION INDICATORS | CMC DAYMARK CORPORATION (US) | 2003-10-16 | — | — | WO | claimed |
| WO-2005036109-A2 | INTEGRATING ULTRAVIOLET EXPOSURE DETECTION DEVICES | SEGAN INDUSTRIES, INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| WO-2003085397-A2 | PLURAL INTRINSIC EXPIRATION INITIATION APPLICATION INDICATORS | CMC DAYMARK CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |