Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 3/20 | 0.55 |
| ▸ | MVD | P53602 | 4/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13133478 | 1.00 | BTN3A1 (0.55) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL1542080 | 0.96 | BTN3A1 (0.59) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL28234823 | 0.93 | BTN3A1 (0.57) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL309468 | 0.91 | BTN3A1 (0.47) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL18798621 | 0.88 | LPAR3 (0.53) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL10935345 | 0.88 | LPAR3 (0.53) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL29174378 | 0.86 | BTN3A1 (0.57) | BTN3A1MVDGGPS1FNTAFNTB | |
| SCHEMBL27854174 | 0.86 | LPAR3 (0.62) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL25212129 | 0.84 | LPAR3 (0.60) | BTN3A1MVDLPAR3LPAR1LPAR2 | |
| SCHEMBL6538444 | 0.84 | LPAR3 (0.66) | BTN3A1MVDLPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545555-A2 | COMPOSITIONS AND METHODS FOR TREATING EPITHELIAL AND RETINAL TISSUE DISEASES | Inspire Pharmaceuticals, Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2003072067-A2 | COMPOSITIONS AND METHODS FOR TREATING EPITHELIAL AND RETINAL TISSUE DISEASES | INSPIRE PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |