Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.30 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363030 | 1.00 | CYP3A4 (0.37) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL10410813 | 0.82 | MAPT (0.38) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL10410810 | 0.82 | MAPT (0.38) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL29220213 | 0.78 | CYP3A4 (0.42) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL175899 | 0.78 | — | — | |
| SCHEMBL177943 | 0.77 | CYP3A4 (0.48) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL244797 | 0.76 | — | — | |
| SCHEMBL1839647 | 0.75 | MAPT (0.43) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL6838883 | 0.75 | TSHR (0.39) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL37486 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190728-A | AND LOWER ALKYL 2-HYDROXYIMINOACETATES FROM ALKANOL, CHLORAL, HYDROXYAMINE SALT, LEWIS ACID OR ALKANOL, CHLORAL OXIME BASE, OPTIONALLY CHLORINATING | SHIONOGI & CO., LTD. (JP) | 1980-02-26 | — | — | US | claimed |
| US-20050079979-A1 | Substituted benzoylisoxazoles and the use thereof as herbicides | MULLER KLAUS-HELMUT (DE) | 2005-04-14 | — | — | US | disclosed |
| US-6838415-B1 | Substituted benzoylisoxazoles and the use thereof as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-04 | — | — | US | disclosed |
| US-4190728-A | AND LOWER ALKYL 2-HYDROXYIMINOACETATES FROM ALKANOL, CHLORAL, HYDROXYAMINE SALT, LEWIS ACID OR ALKANOL, CHLORAL OXIME BASE, OPTIONALLY CHLORINATING | SHIONOGI & CO., LTD. (JP) | 1980-02-26 | — | — | US | disclosed |
| US-4190728-A | AND LOWER ALKYL 2-HYDROXYIMINOACETATES FROM ALKANOL, CHLORAL, HYDROXYAMINE SALT, LEWIS ACID OR ALKANOL, CHLORAL OXIME BASE, OPTIONALLY CHLORINATING | SHIONOGI & CO., LTD. (JP) | 1980-02-26 | — | — | US | disclosed |
| US-4190728-A | AND LOWER ALKYL 2-HYDROXYIMINOACETATES FROM ALKANOL, CHLORAL, HYDROXYAMINE SALT, LEWIS ACID OR ALKANOL, CHLORAL OXIME BASE, OPTIONALLY CHLORINATING | SHIONOGI & CO., LTD. (JP) | 1980-02-26 | — | — | US | disclosed |
| US-4014876-A | HYPOGLYCEMIC | SHIONOGI & CO., LTD. (JA) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050079979-A1 | Substituted benzoylisoxazoles and the use thereof as herbicides | CYP4X1, DDT, GLRX3 | CYP3A4 28/4885TSHR 330/4885MAPT 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.