SCHEMBL642497

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL644420	0.89	GCK (0.48)	GCKMAPK1LMNAMAPTTSHR
	SCHEMBL643676	0.88	GCK (0.38)	GCKLMNAMAPTTSHRRAB9A
	SCHEMBL643986	0.87	GCK (0.49)	GCKMAPK1LMNAMAPTTSHR
	SCHEMBL642434	0.86	GCK (0.60)	GCKMAPK1LMNAMAPTTSHR
	SCHEMBL642529	0.84	GCK (0.51)	GCKMAPK1LMNAMAPTTSHR
	SCHEMBL643613	0.84	GCK (0.53)	GCKKDM4EGPR183ALDH1A1GLA
	SCHEMBL643650	0.81	GCK (0.52)	GCKLMNAMAPTTSHRRAB9A
	SCHEMBL644165	0.80	GCK (0.49)	GCKMAPK1KDM4EL3MBTL1ALDH1A1
	SCHEMBL642587	0.80	GCK (0.43)	GCKLMNAMAPTTSHRRAB9A
	SCHEMBL643595	0.79	GCK (0.40)	GCKMAPK1LMNAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.