Pyridine-2,5-Dicarboxylic Acid

Pyridine-2,5-Dicarboxylic Acid

SCHEMBL6425823

O=C(O)c1ccc(C(=O)O)nc1.c1ccncc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 11/20 0.78
P4HA1 P13674 2/20 0.78
MIF P14174 1/20 0.78
ALDH1A1 P00352 3/20 0.55
APP P05067 1/20 0.55
GAA P10253 1/20 0.55
HCAR3 P49019 1/20 0.55
HCAR2 Q8TDS4 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MAPK1 P28482 1/20 0.54
NAPRT Q6XQN6 3/20 0.52
LMNA P02545 1/20 0.52
LDHA P00338 1/20 0.49
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine-2,5-Dicarboxylic Acid SCHEMBL29363410 0.88 P4HTM (1.00) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL70231 0.88 P4HTM (1.00) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL2275972 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL21173963 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL7655946 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL9367780 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL336436 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL9341728 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL11489139 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3
Pyridine-2,5-Dicarboxylic Acid SCHEMBL28522095 0.86 P4HTM (0.95) P4HTMP4HA1MIFALDH1A1HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050244695-A1 vinyl-containing sulfonic acid polymerized in presence of one or more aromatic tetraamino compounds and with one or more aromatic carboxylic acids, their esters, their acid halides or their acid anhydrides; interpenetrating polymer network BASF FUEL CELL GMBH (DE) 2005-11-03 US claimed