Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740616 | 1.00 | GAA (0.60) | GAAKDM4EMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1936838 | 0.98 | GAA (0.58) | GAAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL27638728 | 0.91 | KDM4E (0.58) | GAAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL377687 | 0.86 | KDM4E (0.53) | GAAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL2094800 | 0.86 | GAA (0.53) | GAAKDM4EMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6999773 | 0.83 | GAA (0.50) | GAAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL6925611 | 0.83 | KDM4E (0.61) | GAAKDM4EMAPTKMT2APOLB | |
| SCHEMBL3067731 | 0.83 | GAA (0.45) | GAAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL19262329 | 0.81 | GAA (0.47) | GAAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL15594524 | 0.81 | KDM4E (0.47) | GAAKDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007614-A1 | MONOAMINE OXIDASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 6011 (US) | 2005-01-27 | — | — | WO | disclosed |