Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.64 |
| ▸ | CHUK | O15111 | 4/20 | 0.63 |
| ▸ | EPHA3 | P29320 | 3/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4658944 | 0.92 | IKBKB (0.76) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL4657806 | 0.84 | IKBKB (0.76) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL4657725 | 0.83 | IKBKB (0.71) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL6427692 | 0.80 | IKBKB (0.71) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL13980367 | 0.79 | IKBKB (0.82) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL4659245 | 0.79 | IKBKB (0.71) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL4657138 | 0.78 | IKBKB (1.00) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL4658215 | 0.78 | IKBKB (1.00) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL4657043 | 0.78 | IKBKB (1.00) | IKBKBCHUKEPHA3PDGFRANTRK1 | |
| SCHEMBL4656957 | 0.78 | IKBKB (0.79) | IKBKBCHUKEPHA3PDGFRANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513516-A1 | SUBSTITUTED 3-AMINO-THIENO(2,3-b) PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS ANDPROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103661-A1 | SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |