⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548512 | 0.82 | — | — | |
| SCHEMBL9953874 | 0.82 | — | — | |
| SCHEMBL4455224 | 0.77 | — | — | |
| SCHEMBL2814142 | 0.76 | — | — | |
| SCHEMBL3630273 | 0.75 | — | — | |
| SCHEMBL1501235 | 0.75 | — | — | |
| SCHEMBL8123470 | 0.69 | — | — | |
| SCHEMBL1037697 | 0.67 | — | — | |
| SCHEMBL5378825 | 0.66 | — | — | |
| SCHEMBL283912 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227987-A1 | 11beta-hydroxysteroid dehydrogenase inhibitors | STERIX LIMITED (GB) | 2005-10-13 | — | — | US | disclosed |