Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326514 | 0.90 | MAPT (0.54) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL8680705 | 0.90 | MEN1 (0.56) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL8685128 | 0.90 | MAPT (0.54) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL8682154 | 0.86 | MEN1 (0.48) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL11786792 | 0.82 | MAPT (0.57) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL12855110 | 0.82 | MAPT (0.57) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL8680617 | 0.82 | MEN1 (0.56) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL31408945 | 0.81 | MAPT (0.58) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL22127218 | 0.81 | MAPT (0.58) | MEN1KMT2AGFERMAPTGAA | |
| SCHEMBL22637971 | 0.81 | MAPT (0.53) | MEN1KMT2AGFERMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133391-B1 | THERMOCHROMIC DEVICES | PLEOTINT LLC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-6084702-A | Thermochromic devices | PLEOTINT, L.L.C. (US) | 2000-07-04 | — | — | US | disclosed |