Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 18/20 | 0.57 |
| ▸ | OXGR1 | Q96P68 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719339 | 0.96 | SUCNR1 (0.58) | SUCNR1OXGR1KDM4EMEN1LMNA | |
| SCHEMBL3227810 | 0.82 | SUCNR1 (0.47) | SUCNR1OXGR1KDM4EMEN1LMNA | |
| SCHEMBL30471836 | 0.82 | SUCNR1 (0.57) | SUCNR1OXGR1KDM4EMEN1LMNA | |
| SCHEMBL24193793 | 0.82 | SUCNR1 (0.57) | SUCNR1OXGR1KDM4EMEN1LMNA | |
| SCHEMBL6563211 | 0.80 | SUCNR1 (0.61) | SUCNR1OXGR1KDM4EMEN1LMNA | |
| SCHEMBL2837975 | 0.79 | HDAC1 (0.48) | ASAH1 | |
| SCHEMBL7014475 | 0.78 | SUCNR1 (0.54) | SUCNR1OXGR1LMNA | |
| SCHEMBL20517681 | 0.78 | SUCNR1 (0.49) | SUCNR1OXGR1KDM4EMEN1LMNA | |
| SCHEMBL2842747 | 0.78 | HDAC1 (0.50) | ASAH1 | |
| SCHEMBL6424982 | 0.78 | SUCNR1 (0.48) | SUCNR1OXGR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |