Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.70 |
| ▸ | NMBR | P28336 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | KLK7 | P49862 | 1/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463031 | 0.93 | NMBR (0.64) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL16463033 | 0.93 | NMBR (0.64) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL29397912 | 0.92 | TACR1 (0.82) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL5355362 | 0.92 | TACR1 (0.82) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL16464197 | 0.92 | TACR1 (0.82) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL8697113 | 0.92 | TACR1 (0.82) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL4061921 | 0.92 | NMBR (0.66) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL20509877 | 0.90 | NMBR (0.69) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL21954243 | 0.90 | NMBR (0.69) | TACR1NMBRMAPTGAAHTT | |
| SCHEMBL21954242 | 0.90 | NMBR (0.69) | TACR1NMBRMAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155023-B1 | CHELATING COMPOUNDS AND THEIR COMPLEXES WITH PARAMAGNETIC METALS | BRACCO SPA (IT) | 2005-03-02 | — | — | EP | disclosed |
| US-6509324-B1 | Use as contrast agents in magnetic resonance imaging | BRACCO S.P.A. (IT) | 2003-01-21 | — | — | US | disclosed |
| US-20030013859-A1 | CHELATING COMPOUNDS, THEIR COMPLEXES WITH PARAMAGNETIC METALS | BRACCO S.P.A. (IT) | 2003-01-16 | — | — | US | disclosed |
| US-6403055-B1 | CARBOXYLATED POLYAMINE COMPOUND | DIBRA S.P.A. (IT) | 2002-06-11 | — | — | US | disclosed |
| EP-1155023-A1 | CHELATING COMPOUNDS AND THEIR COMPLEXES WITH PARAMAGNETIC METALS | BRACCO S.p.A. (IT) | 2001-11-21 | — | — | EP | disclosed |
| WO-2001046207-A1 | CHELATING COMPOUNDS, THEIR COMPLEXES WITH PARAMAGNETIC METALS | BRACCO S.P.A. (IT) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013859-A1 | CHELATING COMPOUNDS, THEIR COMPLEXES WITH PARAMAGNETIC METALS | MPI, SLC39A14, LRPPRC | TACR1 1402/4885NMBR 718/4885MAPT 1243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.