Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809472 | 1.00 | KDM4E (0.38) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL12358121 | 1.00 | KDM4E (0.38) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL13270790 | 0.91 | KDM4E (0.36) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL3807341 | 0.88 | KDM4E (0.39) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL3809477 | 0.87 | KDM4E (0.35) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL2158446 | 0.85 | KDM4E (0.42) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL2158072 | 0.84 | KDM4E (0.42) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL2157675 | 0.83 | KDM4E (0.41) | KDM4ENPC1POLBMAPTRAB9A | |
| SCHEMBL2157574 | 0.82 | IKBKB (0.41) | — | |
| SCHEMBL2157540 | 0.80 | KDM4E (0.39) | KDM4ENPC1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881741-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-04-19 | — | — | US | claimed |
| US-6881741-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-04-19 | — | — | US | disclosed |