Bicarbonate

Bicarbonate

SCHEMBL6428174

N.O.O=C(O)O.[NaH]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL3344078 0.94
Bicarbonate SCHEMBL4662241 0.94 CA1 (0.71)
Bicarbonate SCHEMBL867106 0.94
Bicarbonate SCHEMBL9151976 0.94
Bicarbonate SCHEMBL991388 0.94 CA1 (0.71)
Bicarbonate SCHEMBL20212138 0.94 CA1 (0.71)
Bicarbonate SCHEMBL2502923 0.94
Bicarbonate SCHEMBL367726 0.94
Bicarbonate SCHEMBL22749424 0.94
Bicarbonate SCHEMBL2956723 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220054589-A1 Compositions Comprising Antimicrobial Peptides UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-02-24 US claimed
US-5688904-A USING EFFLUENT OF AN IMMOBILIZED CELL OR ENZYME AS CATALYST CALWOOD CHEMICAL INDUSTRIES INC. (US) 1997-11-18 US claimed
US-5610264-A Continuous process for polyaspartic acid synthesis CALWOOD CHEMICAL INDUSTRIES, INC. (US) 1997-03-11 US claimed
CN-109135626-A One kind exempting from roasting and exempts to shine quick-drying fireworks reel glue 浏阳象形精品烟花出口制造有限公司 2019-01-04 CN disclosed
US-6958144-B2 Methods of whitening teeth BRITESMILE DEVELOPMENT, INC. (US) 2005-10-25 US disclosed
EP-1192319-A1 REINFORCED NETWORKED POLYMER/CLAY ALLOY COMPOSITE Alberta Research Council, Inc. (CA) 2002-04-03 EP disclosed
WO-2000073596-A1 REINFORCED NETWORKED POLYMER/CLAY ALLOY COMPOSITE ALBERTA RESEARCH COUNCIL INC. (CA) 2000-12-07 WO disclosed
EP-0861274-A4 CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS CALWOOD CHEM IND INC (US) 1998-10-28 EP disclosed
EP-0861274-A1 CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS Calwood Chemical Industries, Inc. (US) 1998-09-02 EP disclosed
US-5688904-A USING EFFLUENT OF AN IMMOBILIZED CELL OR ENZYME AS CATALYST CALWOOD CHEMICAL INDUSTRIES INC. (US) 1997-11-18 US disclosed
WO-1997018249-A1 CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS CALWOOD CHEMICAL INDUSTRIES, INC. (US) 1997-05-22 WO disclosed
US-5610264-A Continuous process for polyaspartic acid synthesis CALWOOD CHEMICAL INDUSTRIES, INC. (US) 1997-03-11 US disclosed
US-4708805-A SOLUTION OF CITRIC ACID, A POLYCARATIC ACID AND AN ALKYLENEPOLYAMINOPOLYCARBOXYLIC ACID CORPEX TECHNOLOGIES, INC. 1987-11-24 US disclosed