Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5068676 | 1.00 | — | — | |
| Bicarbonate SCHEMBL22800564 | 1.00 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL992942 | 0.95 | — | — | |
| Bicarbonate SCHEMBL3276858 | 0.95 | CA4 (0.55) | — | |
| Bicarbonate SCHEMBL10962533 | 0.95 | CA4 (0.55) | — | |
| Bicarbonate SCHEMBL8723912 | 0.95 | CA4 (0.55) | — | |
| Bicarbonate SCHEMBL9442743 | 0.95 | CA4 (0.55) | — | |
| Bicarbonate SCHEMBL1924435 | 0.95 | — | — | |
| Bicarbonate SCHEMBL176206 | 0.95 | — | — | |
| Bicarbonate SCHEMBL28529664 | 0.95 | CA4 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220054589-A1 | Compositions Comprising Antimicrobial Peptides | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-02-24 | — | — | US | claimed |
| CN-108899536-A | A kind of pulse battery NixAlyMnzO2The preparation method and application of tertiary cathode material | 渤海大学 | 2018-11-27 | — | — | CN | claimed |
| US-5688904-A | USING EFFLUENT OF AN IMMOBILIZED CELL OR ENZYME AS CATALYST | CALWOOD CHEMICAL INDUSTRIES INC. (US) | 1997-11-18 | — | — | US | claimed |
| US-5610264-A | Continuous process for polyaspartic acid synthesis | CALWOOD CHEMICAL INDUSTRIES, INC. (US) | 1997-03-11 | — | — | US | claimed |
| US-20200369652-A1 | PROCESSES FOR PREPARATION OF LIFITEGRAST AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2020-11-26 | — | — | US | disclosed |
| CN-107226882-B | A kind of surface modification molecular blotting solid phase microextraction probe and its preparation and application | 佛山科学技术学院 | 2019-09-13 | — | — | CN | disclosed |
| CN-107416913-B | A kind of spherical cobaltic-cobaltous oxide raw powder's production technology | 湖南中伟新能源科技有限公司 | 2019-02-15 | — | — | CN | disclosed |
| WO-2019026014-A1 | PROCESSES FOR PREPARATION OF LIFITEGRAST AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2019-02-07 | — | — | WO | disclosed |
| CN-107119200-B | A kind of method of waste and old mischmetal fluorescent powder high efficiente callback rare earth element | 桑德（天津）再生资源投资控股有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-108899536-A | A kind of pulse battery NixAlyMnzO2The preparation method and application of tertiary cathode material | 渤海大学 | 2018-11-27 | — | — | CN | disclosed |
| CN-108899536-A | A kind of pulse battery NixAlyMnzO2The preparation method and application of tertiary cathode material | 渤海大学 | 2018-11-27 | — | — | CN | disclosed |
| CN-108165733-A | A kind of method of the more metal synthetical recoveries of nickel, iron, magnesium in silicon magnesium types lateritic nickel ore | 昆明理工大学 | 2018-06-15 | — | — | CN | disclosed |
| WO-2000073596-A1 | REINFORCED NETWORKED POLYMER/CLAY ALLOY COMPOSITE | ALBERTA RESEARCH COUNCIL INC. (CA) | 2000-12-07 | — | — | WO | disclosed |
| EP-0861274-A4 | CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS | CALWOOD CHEM IND INC (US) | 1998-10-28 | — | — | EP | disclosed |
| EP-0861274-A1 | CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS | Calwood Chemical Industries, Inc. (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5688904-A | USING EFFLUENT OF AN IMMOBILIZED CELL OR ENZYME AS CATALYST | CALWOOD CHEMICAL INDUSTRIES INC. (US) | 1997-11-18 | — | — | US | disclosed |
| WO-1997018249-A1 | CONTINUOUS PROCESS FOR POLYASPARTIC ACID SYNTHESIS | CALWOOD CHEMICAL INDUSTRIES, INC. (US) | 1997-05-22 | — | — | WO | disclosed |
| US-5610264-A | Continuous process for polyaspartic acid synthesis | CALWOOD CHEMICAL INDUSTRIES, INC. (US) | 1997-03-11 | — | — | US | disclosed |
| WO-1993010753-A1 | UVA-ABSORBING SUNSCREEN METAL COMPLEXES | RICHARDSON-VICKS, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| US-4708805-A | SOLUTION OF CITRIC ACID, A POLYCARATIC ACID AND AN ALKYLENEPOLYAMINOPOLYCARBOXYLIC ACID | CORPEX TECHNOLOGIES, INC. | 1987-11-24 | — | — | US | disclosed |