Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.50 |
| ▸ | CNR1 | P21554 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428346 | 0.81 | CNR2 (0.41) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6304721 | 0.76 | KDM4E (0.47) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6302527 | 0.75 | KDM4E (0.49) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6305637 | 0.75 | CNR2 (0.48) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15327919 | 0.74 | SMN1; SMN2 (0.54) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6302640 | 0.74 | CNR2 (0.52) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16982382 | 0.73 | CNR2 (0.54) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6302525 | 0.71 | CNR2 (0.48) | CNR2CNR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6310614 | 0.70 | TAAR1 (0.38) | KDM4EALDH1A1PARP1TAAR1 | |
| SCHEMBL17151496 | 0.69 | CNR2 (0.40) | CNR2CNR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949562-B2 | Heterocyclic compounds as ligands of the GABAA receptor | NEUROGEN CORPORATION (US) | 2005-09-27 | — | — | US | disclosed |