Metacresol

Metacresol

SCHEMBL6428357

Cc1cccc(O)c1.Cc1ccccc1O.Oc1ccccc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.86
CYP1A2 P05177 1/20 0.86
ACHE P22303 2/20 0.65
HSD17B1 P14061 2/20 0.46
HSD17B2 P37059 2/20 0.46
TRPA1 O75762 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
TP53 P04637 1/20 0.43
ATM Q13315 1/20 0.43
CA12 O43570 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA1 P00915 1/20 0.42
GLA P06280 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metacresol SCHEMBL11435519 0.96 CYP2C19 (0.86) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
Metacresol SCHEMBL636353 0.96 CYP2C19 (0.86) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
P-Cresol SCHEMBL5555586 0.95 CYP1A2 (0.97) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
Metacresol SCHEMBL9847885 0.95 CYP2C19 (0.78) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
Metacresol SCHEMBL6348111 0.94 CYP2C19 (0.83) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
P-Cresol SCHEMBL15200860 0.93 CYP1A2 (0.93) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
P-Cresol SCHEMBL29404960 0.93 CYP2C19 (1.00) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
P-Cresol SCHEMBL6243247 0.93 CYP2C19 (1.00) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
P-Cresol SCHEMBL31006310 0.93 CYP2C19 (1.00) CYP2C19CYP1A2ACHEHSD17B1HSD17B2
Metacresol SCHEMBL5333179 0.92 CYP2C19 (0.80) CYP2C19CYP1A2ACHEHSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2814342-A2 AEROSOL-GENERATING ARTICLE HAVING AN AEROSOL-COOLING ELEMENT Philip Morris Products S.a.s. (CH) 2014-12-24 EP disclosed
WO-2013120565-A2 AEROSOL-GENERATING ARTICLE HAVING AN AEROSOL-COOLING ELEMENT PHILIP MORRIS PRODUCTS S.A. (CH) 2013-08-22 WO disclosed
US-20050233930-A1 Disinfectant cleaning compositions RECKITT BENCKISER INC. (US) 2005-10-20 US disclosed