Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394183 | 0.88 | DPP4 (0.68) | DPP4DPP8 | |
| SCHEMBL3394182 | 0.88 | DPP4 (0.68) | DPP4DPP8 | |
| SCHEMBL3389639 | 0.83 | DPP4 (0.69) | DPP4CYP2D6KCNH2CYP3A4CYP1A2 | |
| SCHEMBL3389637 | 0.83 | DPP4 (0.69) | DPP4CYP2D6KCNH2CYP3A4CYP1A2 | |
| SCHEMBL3388739 | 0.77 | DPP4 (0.69) | DPP4DPP8 | |
| SCHEMBL3388737 | 0.77 | DPP4 (0.69) | DPP4DPP8 | |
| SCHEMBL18851336 | 0.77 | DPP4 (0.66) | DPP4CYP2D6KCNH2CYP3A4CYP1A2 | |
| SCHEMBL18851717 | 0.72 | DPP4 (0.59) | DPP4CYP2D6KCNH2CYP3A4CYP1A2 | |
| SCHEMBL18851689 | 0.72 | DPP4 (0.59) | DPP4CYP2D6KCNH2CYP3A4CYP1A2 | |
| SCHEMBL15300603 | 0.72 | DPP4 (0.63) | DPP4CYP2D6KCNH2CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070535-A1 | Dipeptidyl peptidase inhibitors | SYRRX, INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070535-A1 | Dipeptidyl peptidase inhibitors | DPP4, DPP3, DPP7 | DPP4 1/4885CYP2D6 188/4885KCNH2 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.