⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269561 | 0.75 | BRD4 (0.35) | — | |
| SCHEMBL15733100 | 0.74 | BRD4 (0.46) | — | |
| SCHEMBL103451 | 0.72 | — | — | |
| SCHEMBL14267986 | 0.70 | — | — | |
| SCHEMBL19112993 | 0.68 | — | — | |
| SCHEMBL15049110 | 0.67 | BRD4 (0.39) | — | |
| SCHEMBL10872294 | 0.66 | KDM4E (0.40) | — | |
| SCHEMBL104286 | 0.65 | — | — | |
| SCHEMBL5473091 | 0.65 | BRD4 (0.42) | — | |
| SCHEMBL10869 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110741019-A | Construction body for specifically recognizing glypican 3 and application thereof | 优瑞科生物技术公司 | 2020-01-31 | — | — | CN | disclosed |
| US-6884879-B1 | Anti-VEGF antibodies | GENENTECH, INC. (US) | 2005-04-26 | — | — | US | disclosed |
| US-20040006018-A1 | Cardiotrophin and uses therefor | GENENTECH, INC. | 2004-01-08 | — | — | US | disclosed |
| EP-0918794-B1 | USES FOR WNT POLYPEPTIDES | GENENTECH INC (US) | 2003-10-15 | — | — | EP | disclosed |
| US-6492331-B1 | NL8 tie ligands homologues | GENENTECH, INC. | 2002-12-10 | — | — | US | disclosed |
| EP-0956041-A1 | USE OF IGF-I FOR THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE AND RELATED INDICATIONS | DALHOUSIE UNIVERSITY (CA) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998011913-A1 | USE OF IGF-I FOR THE TREATMENT OF POLYCYSTIC KIDNEY DISEASE AND RELATED INDICATIONS | DALHOUSIE UNIVERSITY (CA) | 1998-03-26 | — | — | WO | disclosed |