Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.82 |
| ▸ | PTPN2 | P17706 | 12/20 | 0.60 |
| ▸ | PTPRC | P08575 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912292 | 0.94 | PTPN1 (0.73) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3904935 | 0.90 | PTPN1 (1.00) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3906862 | 0.86 | PTPN1 (0.61) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3912375 | 0.86 | PTPN1 (0.63) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3908199 | 0.86 | PTPN1 (0.74) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3910218 | 0.85 | PTPN1 (0.73) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3912291 | 0.83 | PTPN1 (0.85) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3912218 | 0.83 | PTPN1 (0.84) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3907465 | 0.83 | PTPN1 (0.70) | PTPN1PTPN2PTPRCCYP2C9 | |
| SCHEMBL3906627 | 0.83 | PTPN1 (0.76) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |