Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114413 | 0.84 | TSHR (0.38) | TSHR | |
| SCHEMBL20457455 | 0.73 | TSHR (0.36) | TSHR | |
| SCHEMBL11276158 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL24515074 | 0.72 | TSHR (0.34) | TSHR | |
| SCHEMBL6060603 | 0.69 | FFAR1 (0.31) | — | |
| SCHEMBL16556829 | 0.68 | TSHR (0.32) | TSHR | |
| SCHEMBL5520111 | 0.67 | FFAR1 (0.38) | — | |
| SCHEMBL17935623 | 0.67 | TSHR (0.35) | TSHR | |
| SCHEMBL11020441 | 0.67 | SMPD1 (0.37) | TSHR | |
| SCHEMBL13900602 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539127-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017952-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |